Original Research Article

Influence of recent randomized MeVO trials on current practice patterns and future role of MeVO thrombectomy-

Summary:
This international survey of 456 physicians explored global perspectives on endovascular thrombectomy (EVT) for medium vessel occlusion (MeVO) stroke after recent neutral randomized trials. About 19% reported performing more MeVO-EVTs, while 30% performed fewer. Despite the neutral results, 69% still believed EVT benefits selected MeVO patients. Over 90% were equally or more willing to participate in future MeVO-EVT trials, and 65% of prior trial participants reported enrollment bias. Most respondents (64%) anticipated that adjunct intra-arterial thrombolysis will play a major role in future MeVO treatment, highlighting continued interest in refining patient selection and combination therapy strategies.

Impression:
This survey shows enduring confidence among clinicians in EVT for MeVO despite neutral trials. The recognition of enrollment bias and growing interest in adjunctive intra-arterial thrombolysis emphasize an evolving mindset—seeking better trial designs and more tailored treatment strategies rather than abandoning EVT in medium vessel stroke.

From Department of Radiology, Foothills Medical Centre, University of Calgary, University Drive NW, Calgary T2N 1N4, Canada

View at: https://doi.org/10.1177/15910199251389060

INR Journal: Keep up to date with the latest high-quality, peer-reviewed original research articles, reviews, perspectives and correspondence.